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EFFECT OF ETHYLENEDIAMINETETRACETIC ACID ON LEAD AMONG OCCUPATION LEAD HANDLERS IN ENUGU URBAN NIGERIA
ABSTRACT
The effect of Ethylenedianinetetraacetic acid (EDTA) on lead
content of blood has not been worked on in vitro. This led to
carrying out this research. The aims of this research is to ascertain
if EDTA has any effect on blood lead levels if the sample is collected
using an EDTA tube and also to find out if there is any significant
difference in the blood lead levels of the same sample when
collected with an EDTA tube and a non-EDTA tube. Hundred (100)
males who are commercial painters and who have painted for
more than 5 years were recruited for the research. Fifty (50) males
who had nothing to do with lead and lead products were also
recruited to serve as the control group. The blood lead levels of the
test group were significantly higher (p < 0.05) than that of the
control group. The haematological indices were significantly higher
(p < 0.05) in the blood in plainon-EDTA tubes than that in the tubes
containing EDTA. In the haemoglobin concentration, there was a
significant difference (p < 0.05) between that of the fresh blood
and the sequestered blood. The lead concentration was
significantly higher (p < 0.05) in the native blood than the
sequestered blood. From the investigations the EDTA in the tubes
had an effect on the lead already in the blood and the effect was noticed on the haematological parameters.
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